As famously mentioned by Schrödinger, entanglement is “the characteristic trait of quantum mechanics”, and provides physical consequences which are incompatible with any classical interpretation. Because of such incompatibilities, many of the promising applications of quantum theory at the fundamental level may become possible due to the particularities of quantum entanglement, such as quantum key distribution, quantum teleportation and quantum dense code. In this context, it is fundamental to establish ways to create entanglement between two or more systems at long distances. In this seminar, we revise many important historical facts related to entanglement theory and conclude by describing a quantum information protocol, named “entanglement mediation”, which probabilistically entangles two distant particles that have never interacted.